Journal of The Chemical Society of Pakistan Current Impact Factor is 0.698

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To Explore the Effect of Injection Molding Processing Parameters on Crazing in Acrylic Polymers

Plastic manufacturing industry is the fastest growing industry as the demand for plastic products is exponentially growing worldwide. Poly (methyl methacrylate) (PMMA), also known as acrylic glass, is a transparent and rigid thermoplastic. PMMA is highly resistant to UV light. Weathering has an excellent light transmission and unlimited coloring options compared to other transparent plastic and has been used in wide applications such as architecture, automotive and transportation, lighting (LED lights), medical and healthcare, and furniture. Injection molding is the widely used plastic more

Rafiq Ahmed, Asim Mushtaq, Saud Hashmi, Sindhia Abbasi and Zaeem Uddin Ali

Electrochemical and Computational Study of Copper Histidine Complex via Cyclic Voltammetry

L-Histidine regulates body function and involve in the synthesis of hemoglobin, repairing of tissues and strengthens of immune system. In this study, Cyclic Voltammetry (CV) is used with 0.1 M Potassium Chloride as a supporting electrolyte to determine the accurate metal ligand ratio between Cu+2 and L-Histidine. In CV potential window is set between +0.6 to -0.4V to record theVoltammogram. Voltammograms were recorded by varying scan rate from 50mV/s to 300mV/s. Cyclic Voltammetry is used to analyzed the interfacial performance of the complex and repeated CyclicVoltammograms (07 cycles) were more

Atya Hassan, Sana Gul, Taswar Ali Chandio and Muhammad Ali Minhas

Supported Ruthenium Catalysts for Oxidation of Benzyl Alcohol under Solvent Free Conditions

The investigation comprised an evaluation of the use of the catalyst, 1%Ru/TiO2, to oxidize Phenylmethanol into benzenecarbaldehyde. nitrogen adsorption isotherms and transmittance electron microscope (TEM) were deployed to delineate the properties of the supported catalysts. The findings indicated a superior catalytic performance from 1%Ru/TiO2 prepared using sol-immobilization method. No reaction was taken place with blank reaction or with undoped support. This was deemed to be a consequence of the dispersion and loading of Ru on the TiO2.The reaction conditions, i.e., temperature, reaction more

Raiedhah Alsaiari, Moustafa A. Rizk, Esraa Musa, Huda Alqahtani, Fatima Alqadri, Mervat Mohamed, Mabkhoot Alsaiari, Ali Alkorbi, Iman Shedaiwa, Faeza Alkorbi

Hydrophilic Interaction Chromatography with Sulfobetaine Zwitterionic Polymer-Bonded Stationary Phases

A rapid method for simultaneous determination of two statin drugs based on zwitterionic chromatography (ZIC) had been developed and validated. The development method included examining the effects of chromatographic conditions, including the percentage of organic modifier, pH values, ionic strength of the acetate buffer, and the predominant retention mechanism's experimental determination. Separation developed by two zwitterionic stationary phases (100 mm × 4.6 mm I.D., 3.5µ). The influence of various spacer lengths was being used as an examination tool on atorvastatin and rosuvastatin more

Ali Mohammed Mahir Fahad, Ashraf Saad Rasheed and Hameed Hussien Ali

Preparation, Characterization and Extraction Performance of Rubidium Ions in Water System

In this paper, a valinomycin-functionalized nano-sized magnetic solid-phase extractant (VFE) with the core-shell structure and the Fe3O4 nanospheres as the core is prepared. Related performances are characterized and tested by SEM, PPMS, XRD, FT-IR, TGA, EDS, ICP-MS, and AAS. The optimal extraction conditions are obtained, namely, temperature 50 °C or higher, pH not less than 9.3, and equilibrium extraction time about 35 min. Recycling performance experiments show that the extraction ratio of rubidium ions after 5 extraction-elution cycles is still up to 85.3%. Extraction experiments with the more

Guo-jun Zhang, Hua Fu, Hui-yuan Chen, Huo Liu, Wei-jun Song, Chun-yan Sun, Xin Hu and Yun Zhao

Determination of Puerarin, Daidzein, Baicalin and Wogonin in Composite Preparations by Capillary Electrophoresis

A simple method for the simultaneous determination of four bioactive components (puerarin, daidzein, baicalin, and wogonin) in composite preparations by microemulsion capillary electrophoresis with UV detection has been developed for the first time. A running buffer composed of 8% acetonitrile + 4% microemulsion(3.24% n-heptane + 13.24% sodium dodecyl sulfate (SDS) + 26.44% n-butanol + 57.08% distilled water in weight ratio) + 20 mM borax solution was found to be the most suitable for this separation. The limits of detection for four analytes were over the range of 0.50 - 1.2 μg ml-1. In the more

Cunhong Li and Yan Xu

Metabolomic Profiling of Different Maca Color Types Using Nuclear Magnetic Resonance Spectroscopy and Multivariate Data Analysis

This study aimed to explore significant differences in chemical composition among maca (Lepidium meyenii Walp.) types with different colors in Yunnan province, China. 1H-NMR spectroscopy, in combination with principal component analysis and partial least squares discriminant analysis, was used to investigate the compounds responsible for compositional differences. Different maca color types in Yunnan were clearly distinguished by 11 differential metabolites. Furthermore, network pharmacology results showed that 30 active components were related to Alzheimer’s disease. Nine intersecting more

Jingwei Lv, Chunnan Li, Nanxi Zhang, Kaiyue Z., Xiaochen Gao, Na Li, Lingwen M., Yinping Y., Hui Zhang and Jiaming Sun

Determination of Pka Values of Antidiabetic Drugs from Mobility Data and Pharmaceutical Analysis by Capillary Electrophoresis

In this study, the dissociation constants of six antidiabetic drugs (rosiglitazon maleate, pioglitazone, glimepride, glibenclamide, gliclazide and glipizide) have been calculated by capillary electrophoresis (CE) technique in water from the mobilities of compounds at several pH values. The dissociation constant values of antidiabetics had been checked with the ones formerly decided withinside the literature and additionally with the statistics expected through the SPARC on-line calculator and ACDLAB. Also, easy, precise, green, accurate and completely validated CE technique for the analysis more

Senem Şanlı, Seyfi Sardogan, Ayşe Özdemir and Barış Atalay

In-silico, Antioxidant and Antiepileptic Effect of N(2,3-methylenedioxy-4benzoyloxy-phenthylamine)-3,4-dimethyl-1, propanoamide Derivatives

Epilepsy is a severe neurological illness that affects millions of people the globally and is characterized by unpredicted and intermittent seizures.This research aimed to investigate the antiepileptic and antioxidant properties of papaverine derivatives using in-silico, in-vitro, and in-vivo methods.Epileptic seizure was induced in Swiss albino mice of either gender by administering PTZ (pentylenetetrazol). The antioxidant potential of test compounds was computed using previously published DPPH assay methods with minor modifications, while In-silico experiments were conducted using Auto-dock more

G.A. Miana, M. Kanwal, S. Maqsood, Z. Tariq, F. Ali Shah, H. Saddam, M. Umar Farooq and Arif U. Khan

Investigation of Acrylamide Based Hydrogels as L-Dopa and L-Tyrosine Drug Release System

Acrylamide-based hydrogels exhibit significant volume migration in response to physical and chemical stimuli. These properties make their use as drug delivery systems widespread. In the study, acrylamide-based hydrogel structures were synthesized to be used as two prodrugs known as L-Dopa and L-Tyrosine carrier and release system. Fourier-transform infrared (FTIR) spectroscopy, scanning electron micrography (SEM), Image J program were used to evaluate the structure-property relationship of the synthesized hydrogels and swelling studies were performed. The maximum swelling capacity of the more

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