Lorazapam reacts with alizarin sulphonic acid (sodium salt) to give a pink colored complex, after heating at 50oC for 15S having maximum absorbance at 530 nm. The reaction is selective for lorazepam with 0.01mg/10 ml as visual limit of quantization and provides a basis for a new spectrometric determination the reaction obeys beer’s law from 0. 01to 3 mg/10 ml of lorazepam and the relative standard deviation is 0.68%. the quantative assessments of tolerable amounts of other drugs not interfering are also studied.
A A KAZI ,T AMAN ,R NAZIR ,A A TAHIR ,S G AKBAR ,
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