Condensation of 6-chloro-2-hydrazinoquinoline (1) with monosaccharides 2a-e gave the corresponding sugar hydrazones 3a-e which upon acetylation gave the corresponding acetates 4f-j. Cyclization of 3a-e using iron (III) chloride afforded the acyclic nucleosides of triazoloquinolines 5a-e which were also acetylated to give6f-j. Compound 1 was also condensed with aldehydes and isatin to give the corresponding hydrazones 7-10. Reactions of 1 with ethylchloroformate, phthalic anhydride, acetyl acetone and tosyl chloride were also investigated. All compounds were screened for their antimicrobial activity against gram-positive and gram-negative bacteria.
NADJET REZKI ,JEHAN ABD EL RAZEK HASANEN ,MOHAMED ABD EL_LATIF ZEIN ,SAYED HELMYEL ASHRY ,EL SYED ISMAIL IBRAHIM ,
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