SYNTHESIS AND FUNGICIDAL ACTIVITY OF SOME NEW OF 2,4-DICHLOROBENZOIC ACID 5-SULFONYL AMINO-ACID DERIVATIVES

2,4-Dichlorobenzoic acid reacts with chlorosulphonic acid to yield the corresponding sulphonyl chloride (1). Subsequent condensation with nucleophiles afforded sulphonyl derivatives (2-11), which are used for the synthesis of methyl esters (12-18), the corresponding hydrazide (19-22) and the dipeptide derivatives (23-36). The spectral data of the synthesized compounds (2-36) and the results of preliminary biological screeing are briefly discussed

RAGAB A EL SAYED ,M F BADIE ,F A KORA ,N S KHALAF ,