Synthesis, Characterization and Biological Screening of Ni(II), Co(II) and Cu(II) Complexes with Schiff Base Ligand: N,N'-Bis[1-(4-chlorophenyl)ethylidene]ethane-1,2-diamine

The Schiff base ligand (SBL), N,N'-Bis[1-(4-chlorophenyl)ethylidene]ethane-1,2-diamine (L), was synthesized by condensation of 4-chloroacetophenone with ethylenediamine which was then employed for the synthesis of complexes (1-3) with transition metal(II) ions. The characterization of these compounds was performed by CHN analyses, spectroscopic (1H-NMR, 13C-NMR, IR and MS) and molar conductance data. The structure of L was further confirmed by using XRD. On the basis of electronic spectra and magnetic moment data, an octahedral geometry was proposed for all synthesized complexes (1-3). The conductivity data was used for the confirmation of non-electrolytic nature of these complexes. The Schiff base ligand had a lower antibacterial activity and lethality to shrimp larvae than its complexes (1-3).

Muhammad Aslam, Itrat Anis, Zahra Noreen, Asad Gulzar and Muhammad Tahir Hussain