In this study, the electronic theory of ion-pair chromatography has been extended to include the role of organic modifier. This approach has increased the possibility to use organic modifier in the improvement of separation of ionic, non-ionic and ionized substances. The results accumulated shows that both the slope and the intercept of In K'vs. organic modifier concentration plot are predicted to increase the oppositely charged and to decrease for similarly charged solute ions.
M A CHIPPA ,S A ARBANI ,M Y KHAHAWER ,A RAZAK SOMO ,G ALI QURESHI ,
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