4-Alkyl(aryl )-3-(N-p-tolylcarbamido)-6-bromo-3,4-dihydrocoumarins (2) have been prepared by action of Grignard reagents on 3 (N-p-tolyl-carba-mido)-6-bromocoumarin (1). 4, a-substituted acetic acid derivatives (3, 4 and 5) have been prepa red by Mi chae 1 condensa t i on of (1) wi th d i ethy1 malonate and ketones in presence of sodium ethoxide. But Michael condensation of (1) with diethyl malonate, ethyl acetoacetate or with ketones in presence of amines at 170-180° gave benzopyrano (3,4-c)-pyridine tri(or di)-ones (7,8,9,10 and 11). (1) reacted wi th acetyl acetone in presence of amines at the boiling point of the mixture or at room temperature to give 3,4,5,6-tetrahydro-1,3 benzoxazocines (12). The structures assigned are supported by elemental analysis and spectral data.
N El JADY ,R M SALEH ,G H SAYED ,H M MOSA ,
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