The hydrolysis of the compound, of Methyl-2-[2’-oxo-3’-(2”-chloro-6”-fluorophenyl)propyl]benzoate has been studied spectrometrically in the presence of hydroxide ions in aqueous, 25% and 50% (V/V) EtOH-H2O mixtures. The dependence of pseudo-first order rate constant kobs on hydroxide ion concentration is fitted by the expression kobs =ke = k1[OH] = k2[OH]2, showing the formation of mononionic and dianionic tetrahedral intermediates during the course of reaction. The magnitude of ko shows significant participation of solvent in the reaction mechanism which goes on decreasing with increasing concentration of ethanol in the solvent mixture. The hydrolysis of methyl-2-benzoylmethyl-benzoate has also been studied in aqueous medium in the presence of different hydroxyl ions concentrations and results were compared with the former ester.
N H RAMA ,H B AHMAD ,M A MALANA ,
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