trans-Diphenyl-4-acrylic acid has been synthesized from diphenyl-4-earboxaldehyde which has been prepared by a new route starting from diphenyl. Diphenyl was iust nitrated. The 4-nitro derivative was separated from its 2-isomer and reduced to the amino compound. The iodo derivative of diphenyl was prepared from the amino compound through its diazonium salt and converted to the aldehyde through its Grignard reagent. The aldehyde was then condensed with malonic acid to get the trans-diphenyl-4-acrylic acid. The dibromide of the ethyl ester of this acid was then prepared and subjected to dehydrobromination to get diphenyl-4-propiolic acid which was reduced catalytically to give cis-diphenyl-4-acrylic acid.
S A FASEEH ,M YOUNAS ,S M YOUNAS ,
You can use below filter to find your desired issue