SOME REACTIONS OF 6-CHLORO-2-METHYL 4H-1-BENZOPYRAN-4-ONE .2.

6-Chloro-2-methyl-4-H-1-benzopyran-4-one (1) gave the isoxazole derivative (2a) on reaction with hydroxylamine hydrochloride. The action of hydrazine and phenylhydrazine on (1) resulted in pyrazole derivatives (3a) and (3b) respectively. The reactivity of (1) with ethyloxalate and aromatic nitroso compounds have been investigated. Phthalide (8a) derived from the chromone (1) was synthesised and rearranged easily into 1,3-indandione (9) upon refluxing with alcoholic sodium methoxide. Cleavage of (8) with amines and hydrazine hydrate was studied. Thiation of phthalide (8a) with either Lawesson's re-agent or phosphorous pentasulphide yielded the corresponding thione (8c)

ASHRAF A AHMED ,MOUNIR A I SALEM ,ALI G EL SHEKEIL ,HASSAN M F MADKOUR ,A S BABAQUI ,