Nanomaterials, such as Ag-nanoparticles (AgNPs), have recently been shown to have a broad range of applications in the chemical industry, medicine, biology, and many areas. In this work, the effect of nanostructure on the biological efficiency of prepared surfactants (R10, R12) based on the benzamide group was reported. FTIR and 1HNMR spectra were collected to confirm the structure of these surfactants. In addition, the nanostructures of the prepared surfactants assembled on Ag-nanoparticles (AgNPs) were investigated using UV and TEM techniques. Moreover, the antimicrobial properties of the prepared surfactants and their associated nanostructures were studied. The results showed that, with the exception of Pseudomonas aeruginosa and Escherichia coli, the antibacterial effectiveness of R12AgNPs against all bacteria was better than R12. In contrast, the antibacterial activity of R10AgNPs against all bacteria was lower than R10. This might be explained by the fact that AgNPs were effective on the manufactured surfactant's CMC (R10), which decreased the amount of surfactant molecules at the cell membrane and decreased the antibacterial activity. The outcomes showed that the cationic surfactants (R10, R12) that were synthesized favored AgNP dispersion and enhanced their activity.

Eid M. S. Azzam, Abdallah R. Ismail, Khalaf M. Alenezi, Hani El Moll Lassaad Mechi, and Walaa I. El-sofany