The petroleum ether soluble and insoluble fractions of the methanol extract of air dried stem extract of Daphne mucronata and a pure compound daphnin obtained from the more active petroleum ether insoluble fraction were evaluated for the pro-neurogenic activity on cortical and hippocampal primary cell cultures prepared from the neonatal mice brain. It showed significant proliferation of the cells as assessed by MTT assay


Perveen Bano, Kanwal Iftikhar, Kinza Rafi, Bina Shaheen Siddiqui, Shabana Usman Simjee, Sabira Begum