A new improved first order derivative spectrophotometric method is developed for the simultaneous determination of Temazepam in pure and pharmaceutical samples. Absolute alcohol is used as a solvent through out the study. Temazepam reacts with 0.01% alizirine to give a red-purple colour complex having maximum absorbance at 521.9nm. the colour reaction obeys Beers Law from 4.0-200.0mg/ml of temazepam. The correlation coeffincient is 0.99 and relative standard deviation is 0.84%. the quantitive assessment of tolerable amount of other drugs was also studied. The proposed method can be successfully applied for the quality control of pure tempazepam and in pharmaceutical dosage. This method is simple, reliable and reproducible.


N YAQOOB ,S I KHAN ,M A KASHMIRI ,