CO hydrogenation on the cobalt catalyst with Titania support (Co/TiO2) withoutreduction condition and with a fixed-bed differential cylindrical reactor was kinetically studied.Internal and external mass transfer resistances of the porous catalyst are low and neglected inexperimentations. Models have been developed using Langmuir-Hinshelwood-Hougen-Watson(LHHW) theory based on carbide and enolic mechanisms. Models have compared with experimentaldata according to Levenberg-Marquardt algorithm. The best model (-Rco = kPH2/ (1 + aPco)2 ) isselected because of good agreement with experimental data. Absorption step and hydrogendissociation on surface of the catalyst is considered as a rate determination, simultaneously.Activation energy and enthalpy of the carbon monoxide consumption were obtained 82.3 kj/mol andthe 57.9 kj/mol, respectively.