A method is described based on the complexation of mefenamic acid with copper(II) amine sulpahte and extraction of complex in chloroform. The copper is back extracted with nitric acid. The copper content in aqueous phase is determined by flame atomic absorption spectrometry (FAAS). The concentration of copper is proportional to mefenamic acid. The linear calibration curve was obtained with 30-241 ug\ml, with detection limit S ug/ml. The method was applied for the determination of mefenamic acid in pharmaceutical preparations.
F M A RIND ,T M JEHANGIR ,M Y KHUHAWAR ,
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