Globin prepared from hemoglobin of the patas monkey (Erythrocebus patas) was separated into 0< and (3 polypeptide chains by chromatography on a eM 52 column .. After 8-aminoethylatiol), both chains were digested with trypsin and the amino acid sequences of thc tryptic peptides obtained were analyzed. Further, the order of these tryptic peptides in each ,chain was deduced from their homology with the primary structures of a and (3 chains of human adult hemoglobin. Comparing the primary structures of the a and (3 chains of adult hemoglobin of the patas monkey thus obtained with those of human hemoglobin, 5 amino acid substitutions in the a chains and 7 in the (3 chains were recognized.
K FUKHUSHIMA ,M KUWAHARA ,T MAITA ,M GOODMAN ,G MATSUNDA ,N AIZAWA ,
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