Some new derivatives of Imipramine[lO,ll-Dihydro-N, N-dimethyl( -5H-dibenz (b,f) azepine-5-Propanamine)] and Chloroquine [7-chloro-4-(4-diethylamino-l-methyl butyl amino quinoline)]

von Braun (BrCN) reaction and its extension carried out on imipramine resulted in the formation of N-cyano, N-amido and N-dimethyl amino-(diamine) derivatives. On the other hand, chloroquine on reaction with BrCN yielded three cyano derivatives. All these derivatives have been characterized through spectral studies.

B S SIDDIQUI ,S S AHMAD ,S SIDDIQUI ,S I HAIDER ,