4H-1-Benzopyran-4-ones (Chromones are proved to be of special importance in medicine as stimulants of the central nervous system, spasmolytics, coronary dilators, inhibitors for the growth of human cancer cells, reductants for blood pressure, diuretics, antiallergic, antibiotics and cardiovascular agents. In the course of the present work several new derivatives containing the chromone moiety were prepared. Some of their reactions were investigated in the hope of obtaining new compounds having biological activities. The reactivities of chromone nucleus towards cycloaddition reactions under Diels- Alder conditions, nucleophilic and electrophilic reagents, photocyclodehydrogenation and thiation have been investigated.


H M F MADKOUR ,A S BABAQUI ,A A HAMED ,A G EL SHEKEIL ,M A I SALEM ,